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Biomark Med ; 14(10): 827-837, 2020 07.
Article in English | MEDLINE | ID: covidwho-506060

ABSTRACT

Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivors were compared. Results: An increase in the severity of COVID-19 pneumonia was positively associated with lower levels of platelets and albumin (all p < 0.05). In the critical group, the plasma levels of albumin continued to have a significant association for the risk of nonsurvivors (p < 0.05), even after adjusting for confounding factors. Conclusion: Albumin levels could be used as an independent predictor of the risk of nonsurvivors in critically ill patients with COVID-19.


Subject(s)
Betacoronavirus , Coronavirus Infections/blood , Coronavirus Infections/diagnostic imaging , Critical Illness , Pneumonia, Viral/blood , Pneumonia, Viral/diagnostic imaging , Serum Albumin/metabolism , Aged , Biomarkers/blood , COVID-19 , Coronavirus Infections/mortality , Critical Illness/mortality , Female , Humans , Male , Middle Aged , Pandemics , Pneumonia, Viral/mortality , Predictive Value of Tests , Retrospective Studies , Risk Factors , SARS-CoV-2
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